Pete Ploszek as Leonardo

Alan Ritchson as Raphael

Jeremy Howard as Donatello

Noel Fisher as Michelangelo

Megan Fox as April O'Neil

Stephen Amell as Casey Jones

Will Arnett as Vernon Fenwick

Laura Linney as Chief Vincent

Tyler Perry as Baxter Stockman

Brian Tee as Shredder

Gary Anthony Williams as Bebop

Stephen Farrelly as Rocksteady

Peter Donald Badalamenti II as Splinter

Tony Shalhoub as Splinter (voice)

Brad Garrett as Krang (voice)

Opal Alladin as Security Officer

Brittany Ishibashi as Karai

Connor Fox as Trevor

Alessandra Ambrosio as Self

Stan Demidoff as Uniformed Cop

Jill Martin as Self

Greg Hildreth as Security Guard

Dean Winters as Bartender

Antoinette Kalaj as Hostess

Alice Callahan as Attractive Detective

Jane Wu as Jade

Steve Lacy as News Anchor

Carmelo Anthony as Self

DeAndre Jordan as Self

JJ Redick as Self

Matt Barnes as Self

Austin Rivers as Self

Langston Arnold Galloway as Self

Shane Larkin as Self

Lou Amundson as Self

Andrea Bargnani as Self

Quincy Acy as Self

Courtney L. Kirkland as Referee

Justin Van Duyne as Referee

Joslyn Brewster as Bumbleebee

Robert Clohessy as Deputy Warden Hamlett

Alexis Suarez as Officer

John Palladino as Officer

Meredith Travers as Schoolgirl

Edwin J. Birmingham as NYPD ESU

Paul Teutul, Jr. as Corrections Officer

Kevin Eastman as Pizza Delivery Guy