Jared Leto as Nemo Nobody (Adult / Old)

Sarah Polley as Adult Elise

Diane Kruger as Adult Anna

Linh-Dan Pham as Adult Jean

Rhys Ifans as Nemo's Father

Natasha Little as Nemo's Mother

Toby Regbo as Nemo age 16

Juno Temple as Anna age 15

Allan Corduner as Dr. Feldheim

Daniel Mays as Young Journalist

Clare Stone as Elise age 15

Audrey Giacomini as Jean age 15

Thomas Byrne as Nemo age 9

Laura Brumagne as Anna age 9

Noa De Costanzo as Nemo age 5

Léa Thonus as Elise age 9

Anaïs Van Belle as Jean age 9

Harold Manning as TV Host

Pascal Duquenne as Henry

David Schaal as Thug 1

Laurent Capelluto as Man in Black

Harry Cleven as Man in Black 2

Andrew Simms as Showroom Man

Ben Mansfield as Stefano age 22-40

Emily Tilson as Eve

Roline Skehan as Joyce

Anders Morris as Noah

Nathan Boydell as Paul

Vincent Dupont as Michael

Jenna Wheeler-Hughes as Showroom Girl

Valérie-Marie Chadelaud as Showroom Woman

Stéphane Thiry as Male Nurse 1

Bruno Verstraete as Male Nurse 2

Alice van Dormael as Angel of Oblivian 1

Juliette Van Dormael as Angel of Oblivian 2

Tedd Dillon as Texan Man

Melanie Doerr as Texan Woman

Talya Rubin as Shy Woman

Vito DeFilippo as Shy Man

Corey Cleve Bentivegna as Boy of Shy Couple

Sandrine Laroche as Desillusioned Woman

Olivier Bony as Desillusioned Man

Laura Van Hove as Teenage Girl

Jack Proudlove as Teenage Boy

Marc Zinga as Gay Man 1

Martin Swabey as Gay Man 2

Philippe Godeau as Golf Player / Sad Man

Sarah Gravel as Sad Woman

John Canoe as Mohawk Man

Donna Kanerahtenha Jacobs as Mohawk Woman

Fujio Ishimaru as Japanese Gardener

Robin Carette as Nemo 18 months

Hugo Harold-Harrison as Pool Instructor

Sylvie Olivé as Family Mars Mother

Stéphane Taillasson as Famly Mars Father

Jules Taillasson as Family Mars Son

Jan Hammenecker as Shoe Factory Director

Serge Larivière as Shoe Lace Supplier

Leni Parker as Teacher

Katharina Pejcic as Anna's Daughter

Alexander Türk as Anna's Son

Tanya Trombetta as Anna's Friend

Lola Pauwels as Young Stefano's Girlfriend

Daniel Brochu as Peter

Louise Sophia Engel as Nemo & Anna's Daughter

Aaron Landt as Nemo & Anna's Son

Christelle Cornil as Coma Nurse 1

Tawny Andersen as Coma Nurse 2

Christophe Beaucarne as Villa Owner

Jules Eerdekens as Pool Maintenance Collegue 1

Philippe Lévy as Pool Maintenance Collegue 2

Renaud Alcalde as Spaceship Neighbour 1

Dominique Warnier as Spaceship Neighbour 2

Catherine Demaiffe as Tender Nurse

Pierre Chaves as Hotel Entrance Guard

Nicholas Beveney as Black Man Airport

David Kennedy as Thug 2

Josselin Moinet as Morgue Policeman

Virginie Bordes as Continuity Girl

Carlo Mestroni as Police Officer

Nicolas Ross as Anna & Peter's Son

Marie-Ève Beauregard as Anna & Peter's Daughter

Manfred Andrae as Anna's Neighbour

Thi-Mai Nguyen as Prehistoric Pregnant Woman

John Churchill as Boy on Slide

Barney as Bear (uncredited)