Laurence Fishburne as Vaughn 'Dap' Dunlap

Giancarlo Esposito as Julian 'Dean Big Brother Almighty' Eaves

Tisha Campbell as Jane Toussaint

Ossie Davis as Coach Odom

Joe Seneca as President Harold McPherson

Art Evans as Cedar Cloud

Ellen Holly as Odrie McPherson

Bill Nunn as Grady

Spike Lee as Darrell 'Half-Pint' Dunlap

Kyme as Rachel Meadows

Joie Lee as Lizzie Life

Samuel L. Jackson as Leeds

Jasmine Guy as Dina

Cassi Davis as Paula

Gregg Burge as Virgil Cloyd

Kasi Lemmons as Perry

Branford Marsalis as Jordan

James Bond III as Monroe

Roger Guenveur Smith as Gammite Yoda

Kadeem Hardison as Edge

Eric Payne as Booker T.

Anthony Thompkins as Doo-Doo Breath

Guy Killum as Double Rubber

Dominic Hoffman as Mustafa

Kirk Taylor as Sir Nose

Kevin Rock as Mussolini

Erik Dellums as Slim Daddy

Darryl M. Bell as X-Ray Vision

Rusty Cundieff as Chucky

Cylk Cozart as Dr. Feelgood

Tim Hutchinson as Lance

Leonard L. Thomas as General George Patton

Alva Rogers as Doris Witherspoon

Delphine T. Mantz as Delphine

Terri Lynette Whitlow as Terri

Tanya Lynne Lee as Tanya

Jacquelyn Bird as Jacquelyn

Traci Tracey as Traci

Sharon Ferrol-Young as Sharon

Laurnea Wilkerson as Laurnea

Stephanie Clark as Stephanie

Eartha Robinson as Eartha

Angela Ali as Velda

Jhoe Breedlove as Kim

Paula Jean Brown as Miriam

Tyra Ferrell as Tasha

Karen Owens as Deirdre

Michelle Whitney-Morrison as Vivian

Greta Martin as Greta

Sharon Owens as Sharon

Frances Morgan as Frances

Monique Mannen as Monique 'Mo-Freak'

Cinqué Lee as Buckwheat

Toni Ann Johnson as Muriel

Paula Birth as Carla

Tracy Robinson as Roz

A.J. Johnson as Cecilia

Edward G. Bridges as Moses

Dennis Abrams as Eric

Albert B. Cooper IV as Spoon

Tracy Lewis as Counter Girl

Kelly Woolfolk as Vicky

Florante P. Galvez as Student in Bathroom

Bill Lee as Phil Hyman Quartet - Bass

Consuela Lee Morehead as Phil Hyman Quartet - Piano

Harold Vick as Phil Hyman Quartet - Saxophone

Joe Chambers as Phil Hyman Quartet - Drums

Gregory 'Sugar Bear' Elliott as EU Band - Bass / Vocals

Keith John as Singer at Coronation

Ricky Gordon as Marching Band Snare Drummer and Coordinator of The Mission College Marching Band (uncredited)

Leslie Sykes as Miss Mission

Michelle M. Bailey as Tina / Girl in Window