Robert De Niro as Joseph 'Jacknife' Megessey

Kathy Baker as Martha Flannigan

Ed Harris as David 'High School' Flannigan

Ivar Brogger as Depot Mechanic

Jordan Lund as Tiny

Charles S. Dutton as Jake, Veteran Encounter Group Leader

Bruce Ramsay as Corridor Student

Jessalyn Gilsig as His Girlfriend

Josh Pais as Rick

Gabrielle Carteris as College Girl in Bar

Kirk Taylor as Helicopter Gunner

George Gerdes as Tony

Lois Dellar as Cocktail Waitress

Loudon Wainwright III as Ferretti

Tom Isbell as Bobby Buckman

Sloane Shelton as Shirley

Walter Massey as Ed Buckman

Elizabeth Franz as Pru Buckman

Madison Arnold as Sam, Bartender

Tom Rack as William Green