Ben Stiller as Alex (voice)

Chris Rock as Marty (voice)

David Schwimmer as Melman (voice)

Jada Pinkett Smith as Gloria (voice)

Frances McDormand as Captain Chantel DuBois (voice)

Sacha Baron Cohen as Julien (voice)

Andy Richter as Mort (voice)

Cedric the Entertainer as Maurice (voice)

Jessica Chastain as Gia (voice)

Bryan Cranston as Vitaly (voice)

Martin Short as Stefano (voice)

Paz Vega as Carmen (voice)

Frank Welker as Sonya (voice)

Tom McGrath as Skipper / First Policeman (voice)

Chris Miller as Kowalski (voice)

Christopher Knights as Private (voice)

Conrad Vernon as Mason / Second Policeman (voice)

Vinnie Jones as Freddie the Dog (voice)

Steve Jones as Jonesy the Dog (voice)

Nick Fletcher as Frankie the Dog (voice)

Danny Jacobs as Croupier / Circus Master (voice)

Dan O'Connor as Casino Security / Mayor of New York City (voice)

Eric Darnell as Comandante / Zoo Official / Zoo Announcer (voice)

Stephen Kearin as Fourth Policeman (voice)

Emily Nordwind as Zoo Official (voice)

Asucena Jimenez as Kid in Crowd (voice)