Kate Beckinsale as Selene

Scott Speedman as Michael Corvin

Tony Curran as Marcus Corvinus

Shane Brolly as Kraven

Derek Jacobi as Alexander Corvinus

Bill Nighy as Viktor

Steven Mackintosh as Andreas Tanis

Zita Görög as Amelia

Brian Steele as William Corvinus

John Mann as Samuel

Scott McElroy as Soren

Michael Sheen as Lucian

Sophia Myles as Erika

Richard Cetrone as Pierce

Mike Mukatis as Taylor

Raoul Ganeev as Truck Driver

Andrew Kavadas as Selene's Father

Kayla Levins as Selene's Sister

Attila Lovaghy as Tavern Cop #1

Monica Hamburg as Newscaster

Travis Webster as Cleaner

Kaja Gjesdal as Tanis Vamp #2

Lily Mo Sheen as Young Selene

Adrian Hough as Pilot

Michasha Armstrong as Gunner

Krsy Fox as Tanis Vamp #1

Julius Chapple as French Cleaner Aide