Anthony Hopkins as Dr. Hannibal Lecter

Julianne Moore as Clarice M. Starling

Gary Oldman as Mason Verger

Ray Liotta as Paul Krendler

Giancarlo Giannini as Insp. Renaldo Pazzi

Zeljko Ivanek as Dr. Cordell Doemling

Frankie Faison as Barney Matthews

Francesca Neri as Allegra Pazzi

Hazelle Goodman as Evelda Drumgo

David Andrews as FBI Agent Pearsall

Francis Guinan as FBI Asst. Director Noonan

James Opher as DEA Agent John Eldridge

Enrico Lo Verso as Gnocco

Ivano Marescotti as Carlo

Fabrizio Gifuni as Matteo

Alex Corrado as Piero

Marco Greco as Tommaso

Robert Rietti as Sogliato

Terry Serpico as Officer Bolton

Boyd Kestner as Special Agent Burke

Peter Shaw as Special Agent John Brigham

Kent Linville as Geoffrey, FBI Mail Boy

Don McManus as Asst. Mayor Benny Holcombe

Harold Ginn as Larkin Wayne, I.A.B.

Ted Koch as BATF Agent Bob Sneed

William Powell-Blair as FBI Agent

Aaron Craig as 'Il Mostro' Detective

Andrea Piedimonte Bodini as Agent Franco Benetti

Ennio Coltorti as Ricci

Mark Margolis as Perfume Expert

Ajay Naidu as Perfume Expert

Kelly Piper as Perfume Expert

Judie Aronson as News Reporter

Derrick Simmons as Evelda Drumgo's Bodyguard

Chuck Jeffreys as Evelda Drumgo's Bodyguard

Gano Grills as Evelda Drumgo's Bodyguard

Giannina Facio as Verger's Fingerprint Technician

Renne Gjoni as FBI Agent Michaels

Roberta Armani as Theatergoer