Jeff Bergman as George Jetson / Mr. Spacely (voice)

Grey DeLisle as Jane Jetson (voice)

Trevor Devall as Elroy Jetson (voice)

Tania Gunadi as Gladys (voice)

Tress MacNeille as Rosie the Robot (voice)

Danica McKellar as Judy Jetson (voice)

Frank Welker as Astro (voice)

Eric Bauza as Rolf Rodriguez (voice)

JB Blanc as Usher Robot (voice)

Will Friedle as Mayor Mercury (voice)

Kevin Michael Richardson as Drill Bot (voice)

Paul Wight as Big Show (voice)

Joe Anoa'i as Roman Reigns (voice)

Colby Lopez as Seth Rollins (voice)

Victoria Crawford as Alicia Fox (voice)

Jonathan Fatu Jr. as Jimmy Uso (voice)

Joshua Fatu as Jey Uso (voice)

Stephen Farrelly as Sheamus (voice)

Michael Coulthard as Himself (voice)

Vince McMahon as Himself (voice)

Cody Rhodes as Stardust (voice)

Nick Nemeth as Dolph Ziggler (voice)