Ray Romano as Manny (voice)

John Leguizamo as Sid (voice)

Denis Leary as Diego (voice)

Queen Latifah as Ellie (voice)

Simon Pegg as Buck (voice)

Seann William Scott as Crash (voice)

Josh Peck as Eddie (voice)

Chris Wedge as Scrat (voice)

Karen Disher as Scratte (voice)

Kristen Wiig as Pudgy Beaver Mom (voice)

Eunice Cho as Madison (Diatryma Girl) (voice)

Harrison Fahn as Glypto Boy (voice)

Maile Flanagan as Aardvark Mom (voice)

Jason Fricchione as Adult Molehog Male (voice)

Bill Hader as Gazelle (voice)

Kelly Keaton as Molehog Mom / Shovelmouth Mom (voice)

Joey King as Beaver Girl (voice)

Lucas Leguizamo as Aardvark Boy / Beaver Kid #2 (voice)

Jane Lynch as Diatryma Mom (voice)

Regan Mizrahi as Additional voices / ADR Group

Clea Lewis as Start Mom (voice)

Allegra Leguizamo as Aardvark Girl (voice)

Carlos Saldanha as Dinosaur Babies / Flightless Bird (voice)

Claudia Besso as Additional Voice (voice)

Bea Miller as Additional Voice / ADR Group (voice)

Christian Pikes as Little Johnny (Aardvark Kid) (voice)

Avery Christopher Plum as Beaver Kid #1 (voice)

Joe Romano as Ronald (Shovelmouth Boy) (voice)

Manoela Scarpa Saldanha as Molehog Girl 1 (voice)

Sofia Scarpa Saldanha as Molehog Girl 2 (voice)

Cindy Slattery as Bird (voice)

Matt Adler as Additional Voice (voice)

Steve Alterman as Additional Voice (voice)

Anthony Amorim as Additional Voice (voice)

Holly Dorff as Additional Voice (voice)

Nicole Ehinger as Additional Voice (voice)

David H. Kramer as Additional Voice (voice)

Selenis Leyva as Additional Voice (voice)

Matt McCarthy as Additional Voice (voice)

David McCharen as Additional Voice (voice)

Tim Nordquist as Additional Voice (voice)

Devika Parikh as Additional Voice (voice)

Alexandra Pisacane as Additional Voice (voice)

Jake Schwencke as Additional Voice (voice)

Amanda Scott as Additional Voice (voice)

Johnathan Tchaikovsky as Additional Voice (voice)

Pamala Tyson as Additional Voice (voice)

June Christopher as Additional Voice (voice)

Frank Welker as Momma Dino (voice) (uncredited)